Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06927024

Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Chronic Kidney Disease (CKD)

Led by NYU Langone Health · Updated on 2025-12-31

30

Participants Needed

1

Research Sites

172 weeks

Total Duration

On this page

Sponsors

N

NYU Langone Health

Lead Sponsor

N

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborating Sponsor

AI-Summary

What this Trial Is About

30 patients will participate in a prospective randomized clinical trial to test the safety, tolerability and efficacy of transcutaneous auricular vagus nerve stimulation (taVNS) for autonomic nervous system (ANS) dysfunction in the chronic kidney disease (CKD) stage 3-5 setting.

CONDITIONS

Official Title

Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Chronic Kidney Disease (CKD)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals age 6518 years
  • Diagnosis of Chronic Kidney Disease (CKD) stage 3-5 [estimated glomerular filtration rate 6460 mL/min/1.73m2]
  • Receiving care at NYU Nephrology outpatient practice
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Primary autonomic nervous system disorders (e.g., Parkinson's disease)
  • Arrhythmias
  • Implantable cardioverter-defibrillator (ICD) or pacemaker (PPM) precluding assessment of heart rate variability (e.g., chronic atrial fibrillation)
  • On maintenance dialysis (hemodialysis)
  • Epilepsy
  • Symptomatic bradycardia
  • Presence of implantable defibrillators
  • Presence of a permanent pacemaker
  • Unable to consent
  • Incarcerated individuals
  • Pregnant individuals

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

NYU Langone Health

New York, New York, United States, 10016

Actively Recruiting

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Research Team

Q

Qandeel Soomro, MD

CONTACT

D

David Charytan, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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