Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06827301

Transcutaneous Auricular Vagus Nerve Stimulation for Treating Post-stroke Dysphagia

Led by Campus Bio-Medico University · Updated on 2025-02-14

30

Participants Needed

1

Research Sites

79 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of the present project is to use transcutaneous auricular vagus nerve stimulation (t-VNS) for the treatment of dysphagia in acute stroke patients to improve swallowing function and reduce mortality and disability related to this condition. 30 patients will be randomized into one of the two arms of the study: * REAL: real t-VNS + speech therapy * SHAM: t-VNS placebo + speech therapy. The experimental treatment consists in the association between t-VNS (real or placebo) and speech therapy exercises to improve swallowing functionality. Each patient will undergo a speech therapy rehabilitation session lasting approximately 40 minutes a day for 3 consecutive days, simultaneously with t-VNS on left ear. Swallowing function and clinical conditions will be evaluated before the intervention (baseline, T0), immediately after the intervention (T1) and 3 months after the intervention (T2).

CONDITIONS

Official Title

Transcutaneous Auricular Vagus Nerve Stimulation for Treating Post-stroke Dysphagia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Acute ischemic or hemorrhagic stroke within 7 days of onset
  • Dysphagia diagnosed by FEES with a Fiberoptic Endoscopic Dysphagia Severity Scale (FEDSS) score between 3 and 5
Not Eligible

You will not qualify if you...

  • Pre-existing stroke dysphagia
  • Dementia or other medical conditions that may interfere with the study

AI-Screening

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Trial Site Locations

Total: 1 location

1

Università Campus Bio-Medico di Roma

Roma, RM, Italy, 00128

Actively Recruiting

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Research Team

F

Fioravante Capone, PhD

CONTACT

F

Fabio Pilato, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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