Actively Recruiting

Phase Not Applicable
Age: 18Years - 100Years
FEMALE
NCT05152264

Transcutaneous Electrical Nerve Stimulation for Endometriosis-related Chronic Pain

Led by Göteborg University · Updated on 2025-05-23

40

Participants Needed

1

Research Sites

368 weeks

Total Duration

On this page

Sponsors

G

Göteborg University

Lead Sponsor

V

Vastra Gotaland Region

Collaborating Sponsor

AI-Summary

What this Trial Is About

The study evaluates the effect of TENS (transcutaneous electrical nerve stimulation) as add-on treatment compared with conventional analgesic treatment in patients with endometriosis-related chronic pain. Patients with frequent pain and high pain intensity will be randomized to additional treatment with TENS or conventional treatment for 8 weeks to evaluate the acute effects of TENS treatment (n=40). Patients with endometriosis-related pain that is not frequent or without high pain intensity constitute an external control group. All patients in the study will receive TENS treatment for a total of 16 weeks, for evaluation of long-term effects of TENS treatment.

CONDITIONS

Official Title

Transcutaneous Electrical Nerve Stimulation for Endometriosis-related Chronic Pain

Who Can Participate

Age: 18Years - 100Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Consents to participation in the study
  • Verified endometriosis by laparoscopy or ultrasound
  • Chronic endometriosis-related pain lasting more than 3 months and suitable for TENS treatment
  • Stable endometriosis-specific hormonal drug therapy unchanged for the last 3 months
  • No planned gynecological surgery for endometriosis during the next 7 months
Not Eligible

You will not qualify if you...

  • Unable to understand or use written and spoken Swedish
  • Having a pacemaker, ICD, or other electronic implants
  • Reduced sensation in the painful area
  • Malignant disease with expected survival less than 12 months
  • Alcohol or substance abuse
  • Serious untreated psychiatric illness or psychological condition primarily affecting the patient
  • Participating in another intervention study that may affect outcomes
  • Using more than 90 morphine equivalents per day
  • Currently receiving electro-acupuncture treatment
  • Pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Pain Centre, Department of Anaesthesiology and Intensive Care Medicine Östra, Sahlgrenska University Hospital, Region Västra Götaland

Gothenburg, Sweden

Actively Recruiting

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Research Team

P

Paulin Andréll, MD, PhD

CONTACT

C

Cecilia Ögren, RN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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