Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT04350359

Transcutaneous Tibial Nerve Stimulation for Spinal Cord Injury Neurogenic Bladder

Led by The University of Texas Health Science Center, Houston · Updated on 2026-04-13

120

Participants Needed

2

Research Sites

316 weeks

Total Duration

On this page

Sponsors

T

The University of Texas Health Science Center, Houston

Lead Sponsor

M

MedStar National Rehabilitation Network

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to determine if electric stimulation to the leg, called transcutaneous tibial nerve stimulation (TTNS), can improve bladder outcomes in acute spinal cord injury.

CONDITIONS

Official Title

Transcutaneous Tibial Nerve Stimulation for Spinal Cord Injury Neurogenic Bladder

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 75 years
  • Traumatic or non-traumatic spinal cord injury
  • Admitted to inpatient rehabilitation within 6 weeks of injury
  • Injury level at T9 or above
  • Located in a region that allows follow-up
  • Can speak English or Spanish
Not Eligible

You will not qualify if you...

  • History of genitourinary diseases such as prostate hypertrophy, overactive bladder, or cancer
  • History of central nervous system disorders including prior spinal cord injury, stroke, brain injury, Parkinson's disease, or multiple sclerosis
  • History or symptoms of peripheral neuropathy such as numbness, tingling, burning pain, sensitivity to touch, lack of coordination, or muscle weakness in feet
  • Pregnancy
  • Known injury to the lumbosacral spinal cord, plexus, or pelvis with neuropathy
  • Concern for injury to the tibial nerve pathway
  • Absence of toe flexion or autonomic dysreflexia during electric stimulation test
  • Potential for progressive spinal cord injury including neurodegenerative diseases like ALS, cancer myelopathy, multiple sclerosis, or transverse myelitis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

MedStar National Rehabilitation Hospital

Washington D.C., District of Columbia, United States, 20010

Actively Recruiting

2

TIRR Memorial Hermann Research Center

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

A

Argyrios Stampas, MD

CONTACT

J

Jacqueline Waterson

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

TREATMENT

Number of Arms

3

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Transcutaneous Tibial Nerve Stimulation for Spinal Cord Injury Neurogenic Bladder | DecenTrialz