Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05561595

Transdiagnostic Intervention to Reduce Internalized Health-Related Stigma

Led by University of Florida · Updated on 2026-02-05

195

Participants Needed

1

Research Sites

129 weeks

Total Duration

On this page

Sponsors

U

University of Florida

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Stigma due to health conditions increases disease burden and adversely impacts health. The internalization of health-related stigma is associated with impaired mental health and quality of life. The current project will test the effects of a novel, transdiagnostic, group counseling intervention, and peer support, to determine the optimal method for helping patients cope with health-related stigma, reducing its internalization, and enhancing patient quality of life.

CONDITIONS

Official Title

Transdiagnostic Intervention to Reduce Internalized Health-Related Stigma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosis of at least one stigmatized health condition: obesity, skin disease (including psoriasis, eczema, or vitiligo), cancer (including lung, breast, cervical, colorectal, gynecologic, prostate, or head and neck, including remission), HIV, type 1 or type 2 diabetes, or chronic pain
  • Reported internalization of health-related stigma confirmed by a cutoff score and interview
  • Availability to attend weekly virtual group meetings for 12 weeks, then every other week and monthly through 26 weeks in the evening
  • Willingness to actively participate and share in group meetings
  • Ability to read, speak, and understand English
  • Access to an electronic device with video and internet, or willingness to use provided devices/data if needed
Not Eligible

You will not qualify if you...

  • Receipt of psychotherapy or psychosocial/peer support intervention in the past 3 months (except non-health-focused therapy like family or marriage counseling)
  • Psychiatric hospitalization within the past 6 months
  • Recent medication changes for psychiatric reasons in past 3 months
  • Current active suicidal thoughts or suicide attempt within the past year
  • Current or past thought disorder, psychosis, or unmanaged bipolar disorder
  • Current alcohol or substance use disorder needing immediate treatment
  • Health-related stigma primarily due to mental illness, substance use, or unspecified health conditions
  • No internalized health-related stigma or score below cutoff on stigma measure
  • Unable or unwilling to complete study procedures
  • Severe disease progression or undergoing acute intensive treatment like chemotherapy or radiation; may be eligible after treatment or symptom improvement

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Florida

Gainesville, Florida, United States, 32610

Actively Recruiting

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Research Team

R

Rebecca Pearl, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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