Online Transdiagnostic Cognitive Behavioral Therapy Versus Usual Primary Care for Adults with Common Mental Disorders

What this Trial Is About

Researchers are investigating whether online transdiagnostic cognitive behavior therapy CBT can effectively reduce symptoms in adults with common mental disorders such as anxiety, depression, and stress-related disorders within primary care. This randomized controlled trial compares online transdiagnostic CBT with the usual care provided in primary care settings to see if psychiatric symptoms improve more with the online therapy. The study also aims to explore effects on quality of life, work ability, and neuroticism, as well as cost-effectiveness and sickness absence. Participants are randomly assigned to either online transdiagnostic CBT or primary care as usual. The online CBT is delivered through a secure web platform featuring psychoeducation, worksheets, and exercises arranged in modules with weekly written feedback from a therapist. Some face-to-face or video sessions may be included for support. The usual care group receives standard health services from primary care providers without intervention control by the research team. During the study, participants complete assessments at baseline, weeks 2, 4, 6, 8, 10, and follow-ups at 1 and 2 years. Researchers measure changes in symptoms using the Depression Anxiety Stress Scales-21 DASS-21 and evaluate quality of life, functional impairment, work ability, and sickness absence. Participants provide informed consent, complete baseline assessments, and are monitored through questionnaires and interviews throughout the study, which is planned to continue until 2029.

Transdiagnostic Online CBT Vs. Care As Usual for Primary Care Patients with Common Mental Disorders