Actively Recruiting

Phase Not Applicable
Age: 12Years - 18Years
All Genders
NCT06963463

Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

Led by University of Pittsburgh · Updated on 2025-07-08

90

Participants Needed

2

Research Sites

116 weeks

Total Duration

On this page

Sponsors

U

University of Pittsburgh

Lead Sponsor

C

Children's Hospital of Philadelphia

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to adapt a sleep intervention for individuals representative of all demographic groups, including those who are at the highest risk for suicidal behavior. Sleep difficulties are a promising target for youth with suicidal thoughts and behavior to focus on as a prevention measure. We aim to increase intervention acceptability and impact by adapting it for the adolescent populations at highest risk for suicidal thoughts and behavior. The research project will compare Transdiagnostic Sleep and Circadian Intervention (TranS-C), an evidence based, modularized intervention that targets a range of sleep difficulties to a treatment as usual or control condition including providing weekly sleep feedback reports from data entered into a daily sleep diary and from wearing a sleep sensing, actigraphy watch. Participants in both conditions (TranS-C vs. Sleep Feedback) will wear an actigraphy sleep watch that monitors sleep, and complete daily sleep diaries via smartphone or email. Participants in the TranS-C condition will also wear bright light (BL) and blue blocking glasses each day as well as attend weekly or biweekly sessions with a Sleep Therapist. The sleep therapist will review sleep feedback during sessions.

CONDITIONS

Official Title

Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

Who Can Participate

Age: 12Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adolescents aged 12 to 18 years
  • Current moderate to severe depression with PHQ-9M score of 11 or higher
  • Clinically significant sleep disturbance with PHQ-9M sleep item score of 2 or higher
  • English fluency and literacy sufficient to participate in the study
Not Eligible

You will not qualify if you...

  • Diagnosis of obstructive sleep apnea
  • Diagnosis of restless legs syndrome
  • Diagnosis of psychosis
  • Diagnosis of bipolar disorder
  • Developmental disability that prevents understanding of study procedures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Childrens Hospital of Philadelphia

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

2

University of Pittsburgh

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

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Research Team

B

Brandie George-Milford, MA

CONTACT

B

Beth Hafer

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL) | DecenTrialz