Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT03924791

Transforaminal Epidural Injection in Acute Sciatica

Led by C.L.A.Vleggeert-Lankamp · Updated on 2023-10-19

142

Participants Needed

2

Research Sites

369 weeks

Total Duration

On this page

Sponsors

C

C.L.A.Vleggeert-Lankamp

Lead Sponsor

S

Spaarne Gasthuis

Collaborating Sponsor

AI-Summary

What this Trial Is About

Patients suffering from sciatica are treated conservatively for the first 8 weeks due to the favourable prognosis. This period is preferably extended up to 14-16 weeks after which patients may opt for surgery. However, patients may experience severe discomfort due to pain in the leg which can lead to decreased physical activity and socio-economic problems. An adequate therapy to alleviate symptoms during this period of 'wait-and-see' is lacking. In this study, patients will be randomized to treatment with transforaminal epidural injections or standard oral pain medication.

CONDITIONS

Official Title

Transforaminal Epidural Injection in Acute Sciatica

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with sciatica by GP
  • NRS leg pain of 6 or more on a 10-point scale
  • Symptoms lasting at least 3 weeks and no more than 8 weeks
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Under 18 years of age
  • Condition preventing transforaminal epidural injection
  • Severe scoliosis
  • Received transforaminal epidural injection within 6 months before randomization
  • Previous surgery for sciatica at the same level
  • Surgery for sciatica at another level within one year before inclusion
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Spaarne Gasthuis

Haarlem, Netherlands

Actively Recruiting

2

Spaarne Gasthuis

Hoofddorp, Netherlands

Actively Recruiting

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Research Team

C

Carmen LA Vleggeert-Lankamp, MD Msc Ph.D

CONTACT

E

Eduard JA Verheijen, Bsc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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