Actively Recruiting
Transient Receptor Potential Channels
Led by Penn State University · Updated on 2025-01-17
45
Participants Needed
1
Research Sites
128 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Neurovascular signaling in the skin associated with stimulation of the transient receptor potential (TRP) channels. These channels are stimulated by both temperature and naturally occurring bioactive agents found in mint, chili peppers, garlic, etc. The aim of the study is to examine how topically applied TRP channel agonists including menthol, capsaicin and camphor impact neurovascular responses in the skin.
CONDITIONS
Official Title
Transient Receptor Potential Channels
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 85 years
- Women participants must not be pregnant or breastfeeding
You will not qualify if you...
- Currently pregnant or breastfeeding
- Use of nicotine products exceeding 100 cigarettes or cigars in lifetime
- Known skin allergies, current rash, skin disease, or pigmentation disorders
- Diagnosis of diabetes
- Body mass index over 35 kg/m2
- Use of calcium channel blockers
- Raynaud's syndrome
- Allergy or hypersensitivity to menthol, camphor, capsaicin, or adhesive
- Regular use (more than once a week) of topical analgesics containing menthol, camphor, or capsaicin
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Noll Laboratory
University Park, Pennsylvania, United States, 16802
Actively Recruiting
Research Team
L
Lacy Alexander, Ph.D.
CONTACT
S
Sue K Slimak, R.N.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
6
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