Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06244199

Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

Led by VA Office of Research and Development · Updated on 2025-10-22

250

Participants Needed

2

Research Sites

147 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Cardiac rehabilitation (CR) is a secondary prevention program for patients with cardiovascular disease (CVD). It is especially valuable as CVD increasingly occurs in combination with comorbidity, frailty, and complexities of care that predispose patients to functional decline, disability, and high costs. Still, few Veterans participate in CR, in part because of the difficult logistics to attend. Promising Practice home-based CR (HBCR) was developed to increase CR participation, but many Veterans remain too limited by comorbidity and frailty for participation. A Transition to CR (T2CR) intervention is a face-to-face program that fosters vital skills, education, insights, motivation, and patient-provider relationships conducive to successful HBCR thereafter. This study compares Veterans eligible for CR who are randomized to T2CR intervention versus usual care. Differences in functional capacity, HBCR participation, and healthy days at home are compared over one year. Patients' experiences and providers' perspectives of barriers and facilitators to T2CR are also compared.

CONDITIONS

Official Title

Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female Veterans hospitalized with ischemic heart disease (acute myocardial infarction or stable ischemia)
  • Veterans hospitalized with revascularization (coronary artery bypass grafting or percutaneous coronary intervention)
  • Veterans hospitalized with valvular heart disease (surgical or percutaneous intervention for mitral regurgitation or aortic stenosis)
  • Veterans hospitalized with heart failure (with reduced or preserved ejection fraction)
  • Willingness to consider cardiac rehabilitation as a treatment option, including possible extension of hospitalization by up to 2 days
  • English speaking
  • Able to provide written informed consent
Not Eligible

You will not qualify if you...

  • Unstable medical condition or end-stage disease likely fatal within 12 months
  • Severe cognitive impairment (MiniCog score 0-2)
  • History of addictive or behavioral issues that interfere with safe home-based cardiac rehabilitation
  • Hearing loss interfering with trial participation
  • Living in long-term care prior to hospitalization with no plans to return to independent living

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

Boston, Massachusetts, United States, 02130-4817

Actively Recruiting

2

VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA

Pittsburgh, Pennsylvania, United States, 15240

Actively Recruiting

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Research Team

D

Daniel E Forman, MD

CONTACT

G

Greg A Owens, BA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty | DecenTrialz