Actively Recruiting

Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT06419413

A Translational Study to Describe Clinical Characteristics, Biomarkers and to Identify Phenotypes and Endotypes Associated With Differential Outcomes in Chinese Population

Led by AstraZeneca · Updated on 2026-04-20

355

Participants Needed

21

Research Sites

143 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A Translational Study to Describe Asthma Patient Clinical Characteristics, Treatment Patterns, Biomarkers and to Identify Phenotypes and Endotypes associated with Differential Outcomes that may Support Future Development of Personalised Treatment Strategies in Chinese Population

CONDITIONS

Official Title

A Translational Study to Describe Clinical Characteristics, Biomarkers and to Identify Phenotypes and Endotypes Associated With Differential Outcomes in Chinese Population

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 75 years of age
  • Acceptable FEV1 according to ATS and ERS
  • Compliance with study procedures for all asthma cohorts
  • Physician-diagnosed asthma for at least 3 months before screening visit
Not Eligible

You will not qualify if you...

  • History of alcohol or drug abuse within the past year
  • Pregnant at time of assessment
  • Altered mental status at the time of informed consent
  • Receipt of marketed or investigational biologics within 3 months or 5 half-lives prior to visit 1, whichever is longer
  • History or current upper or lower respiratory infection or symptoms within 2 weeks of baseline assessments
  • Terminal diseases and/or organ failure or participants otherwise considered not appropriate for study participation
  • Receipt of leukotriene receptor antagonists or 5-lipoxygenase inhibitors (e.g., zileuton and montelukast) within 1 month or 5 half-lives prior to baseline, whichever is longer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 21 locations

1

Research Site

Chengdu, Sichuan, China

Actively Recruiting

2

Research Site

Beijing, China

Not Yet Recruiting

3

Research Site

Changsha, China

Not Yet Recruiting

4

Research Site

Dongguan, China

Not Yet Recruiting

5

Research Site

Foshan, China

Not Yet Recruiting

6

Research Site

Guangzhou, China

Not Yet Recruiting

7

Research Site

Hainan, China

Not Yet Recruiting

8

Research Site

Hohhot, China

Not Yet Recruiting

9

Research Site

Huizhou, China

Not Yet Recruiting

10

Research Site

Kunming, China

Not Yet Recruiting

11

Research Site

Nanjing, China

Not Yet Recruiting

12

Research Site

Nanning, China

Not Yet Recruiting

13

Research Site

Shanghai, China

Not Yet Recruiting

14

Research Site

Shenyang, China

Not Yet Recruiting

15

Research Site

Taiyuan, China

Actively Recruiting

16

Research Site

Wenzhou, China

Not Yet Recruiting

17

Research Site

Wuhan, China

Actively Recruiting

18

Research Site

Xi'an, China

Actively Recruiting

19

Research Site

Xuzhou, China

Not Yet Recruiting

20

Research Site

Zhanjiang, China

Not Yet Recruiting

21

Research Site

Zhaoqing, China

Not Yet Recruiting

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Research Team

A

AstraZeneca Clinical Study Information Center

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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