Actively Recruiting
TRansmural hEaliNg Definition in CroHn's Disease (TRENCH 1)
Led by Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives · Updated on 2024-10-08
210
Participants Needed
18
Research Sites
96 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Multicenter prospective cross-sectional study of CD patients, its aim is the construction of an objective and reproducible system for evaluation of Transmural healing in Crohn's Disease (CD). Primary objective : Objective definition of depth or grade of transmural healing in relation to radiologic signs observed during Magnetic Resonance Enterography (MRE) in CD
CONDITIONS
Official Title
TRansmural hEaliNg Definition in CroHn's Disease (TRENCH 1)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Diagnosed with Crohn's Disease for more than 6 months with histological confirmation available in medical records
- Indication for Magnetic Resonance Enterography (MRE) based on routine clinical practice and validated by the treating physician
- Receiving any Crohn's Disease treatment including biologicals or immunomodulators
- Signed and dated written informed consent and privacy authorization prior to study start
- Grade of transmural healing (TH) corresponding to the subject is not already fulfilled as assessed by local reader pair
You will not qualify if you...
- Pregnancy during the study
- Unable to give consent due to physical or mental state
- No written consent provided
- Diagnosis of ulcerative colitis or unclassified inflammatory bowel disease
- Specific postsurgical settings such as ileoanal anastomosis, ileostomy, or colostomy
- Fewer than 3 evaluable ileocolic segments or more than 3 resected ileocolonic segments (excluding ileocecal valve)
- Severe obstructive symptoms
- Symptomatic intra-abdominal abscess
- Contraindication for MRI
- Isolated perianal disease without luminal location
- Poor quality MRE images based on predefined criteria
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 18 locations
1
CHU de Liège
Liège, Belgium, 4000
Not Yet Recruiting
2
CHU Amiens-Picardie (site Sud)
Amiens, France, 80054
Actively Recruiting
3
CHU de Bordeaux - Hôpital Haut-Lévêque
Bordeaux, France, 33600
Not Yet Recruiting
4
APHP - Hôpital Ambroise Paré
Boulogne-Billancourt, France, 92100
Not Yet Recruiting
5
CHU de Clermont-Ferrand - Hôpital d'Estaing
Clermont-Ferrand, France, 63003
Actively Recruiting
6
APHP - Hôpital Louis Mourier
Colombes, France, 92700
Not Yet Recruiting
7
CHRU de Lille - Hôpital Claude Huriez
Lille, France, 59037
Not Yet Recruiting
8
CHU Limoges Dupuytren
Limoges, France, 87000
Actively Recruiting
9
AP-HM - Hôpital Nord
Marseille, France, 13015
Not Yet Recruiting
10
CHU de Montpellier - Hôpital Saint Eloi
Montpellier, France, 34295
Actively Recruiting
11
CHU de Nantes
Nantes, France, 44093
Not Yet Recruiting
12
CHU de Nice - Hôpital l'Archet II
Nice, France, 06200
Not Yet Recruiting
13
CHU de Nîmes - Hôpital Carémeau
Nîmes, France, 30029
Not Yet Recruiting
14
APHP - Hôpital Européen Georges Pompidou (HEGP)
Paris, France, 75908
Not Yet Recruiting
15
Hospices Civils de Lyon
Pierre-Bénite, France, 69475
Not Yet Recruiting
16
CHU Rennes - Hôpital Pontchaillou
Rennes, France, 35033
Not Yet Recruiting
17
CHU de Saint Etienne - Hôpital Nord
Saint-Priest-en-Jarez, France, 42270
Not Yet Recruiting
18
CHRU de Nancy - Hôpitaux de Brabois
Vandœuvre-lès-Nancy, France, 54500
Not Yet Recruiting
Research Team
S
Sophie GEYL
CONTACT
L
Laurent PEYRIN-BIROULET
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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