Actively Recruiting

Phase 2
Phase 3
Age: 18Years - 100Years
All Genders
NCT06621329

Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated Headache

Led by University of California, Davis · Updated on 2025-11-26

40

Participants Needed

1

Research Sites

102 weeks

Total Duration

On this page

Sponsors

U

University of California, Davis

Lead Sponsor

A

Agnes Marshall Walker Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

The study titled \"Transnasal sphenopalatine ganglion block for treatment of acute subarachnoid hemorrhage associated headache\" is a randomized controlled pilot study aimed at evaluating the efficacy of a transnasal sphenopalatine ganglion (SPG) block in addition to standard pain medication for reducing headache severity in patients with acute subarachnoid hemorrhage (aSAH). The study also examines whether this intervention can reduce opioid requirements during hospitalization and upon discharge.

CONDITIONS

Official Title

Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated Headache

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Acute subarachnoid hemorrhage
  • Age greater than 18 years
  • Secured aneurysm
  • Ability to verbalize pain score to clinician, nurse, medical translator, or surrogate decision maker
  • Patient or surrogate decision maker available to provide consent
Not Eligible

You will not qualify if you...

  • Age less than 18 years
  • Unsecured aneurysm
  • Pregnant or lactating
  • Prisoner
  • Unable to verbalize pain score to clinician, nurse, medical translator, or surrogate decision maker
  • Nasal or facial trauma or surgery within the last three months
  • Allergy to lidocaine, bupivacaine, or dexamethasone
  • Patient unable to consent with no available surrogate decision maker

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UC Davis Medical Center

Sacramento, California, United States, 95817

Actively Recruiting

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Research Team

J

Janice Wang-Polagruto, PhD, CCRP

CONTACT

R

Ryan Martin, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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