Open Preperitoneal Inguinal Hernia Repair, TREPP Versus TIPP in a Randomized Clinical Trial.
Willem J V Bökkerink, Giel G Koning, Patrick W H E Vriens...
https://pubmed.ncbi.nlm.nih.gov/34342299/Actively Recruiting
Led by Assiut University · Updated on 2026-06-01
30
Participants Needed
1
Research Sites
13 weeks
Total Duration
Inguinal hernia repair is one of the most common surgeries worldwide, with tension-free mesh repair being the main treatment. This research evaluates the trans rectus sheath extra-peritoneal procedure TREPP, a minimally invasive open approach that accesses the preperitoneal space through the rectus sheath. TREPP aims to avoid interfering with the inguinal nerves, which are believed to play a key role in chronic postoperative inguinal pain CPIP, a common long-term issue after open hernia repair. The study involves patients undergoing the TREPP procedure for inguinal hernia repair. TREPP is performed as a minimally invasive open surgery that uses a medial approach through the rectus sheath to reach the preperitoneal space, avoiding the lateral abdominal wall nerves. This prospective cohort study will monitor patients after surgery to evaluate outcomes such as hernia recurrence and chronic pain. Participants will be followed for about one year to assess the primary outcome of hernia recurrence and the secondary outcome of chronic postoperative inguinal pain three months after surgery. Researchers will monitor patients through clinical follow-up visits and assessments to measure these outcomes. The study aims to better understand the effectiveness and safety of the TREPP technique in reducing long-term pain and hernia recurrence.
CONDITIONS
TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair
M
Mohamad Raafat, MD
F
Faculty of Medicine-Assiut University
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Assiut University
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants undergo the TREPP surgical procedure to repair inguinal hernia and receive immediate post-operative care.
1 surgery visit (in-person)
Duration - Up to 1 year
Participants are monitored for recovery, including assessment of chronic postoperative inguinal pain at 3 months and evaluation of hernia recurrence up to 1 year after surgery.
Approximately 4 to 6 follow-up visits over 1 year
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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https://pubmed.ncbi.nlm.nih.gov/28219816/Assiut University
Lead Sponsor