Actively Recruiting
TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair: A Single-center Prospective Study
Led by Assiut University · Updated on 2026-06-01
30
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Inguinal hernia repair is one of the most common surgeries worldwide, with tension-free mesh repair being the main treatment. This research evaluates the trans rectus sheath extra-peritoneal procedure (TREPP), a minimally invasive open approach that accesses the preperitoneal space through the rectus sheath. TREPP aims to avoid interfering with the inguinal nerves, which are believed to play a key role in chronic postoperative inguinal pain (CPIP), a common long-term issue after open hernia repair. The study involves patients undergoing the TREPP procedure for inguinal hernia repair. TREPP is performed as a minimally invasive open surgery that uses a medial approach through the rectus sheath to reach the preperitoneal space, avoiding the lateral abdominal wall nerves. This prospective cohort study will monitor patients after surgery to evaluate outcomes such as hernia recurrence and chronic pain. Participants will be followed for about one year to assess the primary outcome of hernia recurrence and the secondary outcome of chronic postoperative inguinal pain three months after surgery. Researchers will monitor patients through clinical follow-up visits and assessments to measure these outcomes. The study aims to better understand the effectiveness and safety of the TREPP technique in reducing long-term pain and hernia recurrence.
CONDITIONS
Brief Title
TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults with primary unilateral or bilateral inguinal hernia
You will not qualify if you...
- Strangulated hernias
- Severe comorbidities precluding surgery (ASA Class IV,V)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants undergo the TREPP surgical procedure to repair inguinal hernia and receive immediate post-operative care.
1 surgery visit (in-person)
Duration - Up to 1 year
Participants are monitored for recovery, including assessment of chronic postoperative inguinal pain at 3 months and evaluation of hernia recurrence up to 1 year after surgery.
Approximately 4 to 6 follow-up visits over 1 year
Trial Site Locations
Total: 1 location
1
Faculty of Medicine-Assiut University -Assiut-Egypt
Asyut, Asyut Governorate, Egypt, 71515
Actively Recruiting
Research Team
M
Mohamad Raafat, MD
F
Faculty of Medicine-Assiut University
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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