Comparing Laparoscopic Uterine Lateral Suspension and Transvaginal Sacrospinous Fixation for Pelvic Organ Prolapse Surgery in Women Over 21

What this Trial Is About

Pelvic organ prolapse is a condition that can be treated with conservative methods or surgery. This research evaluates two uterus-preserving surgical approaches for treating pelvic organ prolapse laparoscopic lateral uterine suspension, a modified laparoscopic surgery with expected safety, simplicity, small incisions, and fast recovery and the conventional transvaginal sacrospinous ligament fixation with native tissue repair. The study aims to compare the long-term therapeutic effectiveness, safety, and adverse events of these two approaches. The study involves two groups one undergoing laparoscopic uterine lateral suspension, where a mesh is attached to the uterus and abdominal wall fascia through small incisions, possibly combined with anterior and posterior colporrhaphy and the other undergoing transvaginal sacrospinous fixation, where the uterus is sutured to the right sacrospinous ligament, also possibly combined with colporrhaphy. Both procedures are uterus-preserving surgeries performed under anesthesia. Participants will be followed for up to five years to assess outcomes such as prolapse recurrence, anatomical and functional results, sexual function, and urodynamic measures. Patients will complete questionnaires and undergo evaluations to monitor safety and adverse events over the long term. The total study duration allows for thorough assessment of the efficacy and safety of these surgical treatments for pelvic organ prolapse.

Transvaginal Sacrospinous Hysteropexy Versus Laparoscopic Uterine Lateral Suspension