Comparing Transversalis Fascia Plane Block and Intrathecal Dexmedetomidine for Pain Relief After Cesarean Section

What this Trial Is About

Researchers are evaluating the pain relief effects of two different methods, the transversalis fascia plane TFP block and intrathecal dexmedetomidine, in women undergoing cesarean section. Cesarean section is a common major surgery often performed under spinal anesthesia, which can cause side effects like low blood pressure. Dexmedetomidine is a medication that acts on certain receptors to reduce pain, while the TFP block uses local anesthetic injected near specific nerves to block pain signals in the abdomen. Participants will receive spinal anesthesia with either a bilateral TFP block using bupivacaine injected at the end of surgery, or spinal anesthesia combined with intrathecal dexmedetomidine and a sham block. The TFP block group receives 2.5 mL of hyperbaric bupivacaine 0.5% spinally plus 20 mL of bupivacaine 0.25% in the TFP block. The dexmedetomidine group receives the same spinal anesthetic plus 5 micrograms of intrathecal dexmedetomidine diluted in saline with a sham block. Throughout the study, participants pain levels will be assessed 24 hours after surgery as the main outcome. Researchers will also monitor total morphine use, time to first additional pain medication, blood pressure, heart rate during surgery, and any adverse events within 24 hours. The study includes adult women aged 18 to 40 undergoing cesarean section under spinal anesthesia. Participation involves monitoring and assessments during and after surgery with follow-up on pain and vital signs for one day.

Transversalis Fascia Plane Block Versus Intrathecal Dexmedetomidine in Patients Undergoing Cesarean Section