Actively Recruiting
Transversus Abdominis Plane Block Compared to Local Anesthetic Wound Infiltration in Gynecologic Oncology Surgery
Led by University of Wisconsin, Madison · Updated on 2025-05-16
80
Participants Needed
1
Research Sites
113 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is being done to see if preoperative transversus abdominis plane (TAP) analgesia will provide similar postoperative pain control, hospital length of stay, and postoperative outcomes compared to surgeon-initiated wound infiltration with local anesthetic in participants undergoing laparotomy for gynecologic indications.
CONDITIONS
Official Title
Transversus Abdominis Plane Block Compared to Local Anesthetic Wound Infiltration in Gynecologic Oncology Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to understand and willing to sign written informed consent
- Undergoing exploratory laparotomy via midline vertical skin incision for gynecologic indications at UW Hospital and Clinics
- Older than 18 years
- English speaking and able to provide consent and complete questionnaires
- Able to understand visual and verbal pain scales
- Eligible for TAP block placement as confirmed by the primary surgeon
- No allergies to anesthetic medications
- No prior abdominal reconstructive surgery altering abdominal wall anatomy that would prevent effective TAP block
You will not qualify if you...
- Known allergy to local anesthetics
- History of chronic pain disorders or chronic opioid use exceeding 10mg oral morphine daily for at least 30 days
- History of opioid dependence requiring rehabilitation or opioid antagonists
- Planned exploratory surgery with biopsies only (no organ removal)
- Pregnant, lactating, or planning pregnancy during the study
- Significant liver disease preventing opioid prescription
- Significant kidney disease preventing gabapentin use
- Unsuitable for study participation for other reasons as determined by investigators
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Wisconsin Hospitals and Clinics (UWHC)
Madison, Wisconsin, United States, 53726
Actively Recruiting
Research Team
C
Cancer Connect
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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