Actively Recruiting
Study of Two Pain Relief Methods to Improve Recovery After Open Heart Surgery in Adults Aged 40 to 60
Led by Assiut University · Updated on 2026-07-21
90
Participants Needed
1
Research Sites
4 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating the pain relief effects of two ultrasound-guided regional anesthesia techniques, the transversus thoracic muscle plane block TTPB and the pecto-intercostal fascial block PIFB, in patients undergoing open cardiac surgery. This study focuses on managing the significant pain that occurs after sternotomy, which is a common and painful part of cardiac surgery, especially within the first 24 hours post-operation. Participants will be randomly assigned to one of three groups receiving PIFB, receiving TTPB, or receiving a sham procedure with superficial saline injection. Both PIFB and TTPB blocks are performed intraoperatively using bupivacaine combined with dexamethasone to target nerves supplying the anterior chest wall. The sham group receives superficial needle punctures without active anesthetic injection. During the study, participants analgesic requirements, pain levels, need for rescue pain medication, nausea and vomiting, time to extubation, ICU stay duration, delirium assessment, patient satisfaction, and any complications will be monitored primarily within 24 hours and up to 7 days after surgery. The total participation lasts up to the completion of the postoperative assessments, with the primary outcomes focused on pain control and recovery measures after cardiac surgery.
CONDITIONS
Brief Title
Assessment of a Multimodal Analgesia for Enhanced Recovery After Cardiac Surgery
Research Team
N
Noha H Abdelghany, MD
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here