Actively Recruiting
Traumatic Hemothorax Drainage and Daily Lavage
Led by University of Pennsylvania · Updated on 2026-05-05
20
Participants Needed
1
Research Sites
125 weeks
Total Duration
On this page
Sponsors
U
University of Pennsylvania
Lead Sponsor
C
CLR Medical
Collaborating Sponsor
AI-Summary
What this Trial Is About
This HTX treatment study evaluates the effects of chest tube size and the benefits of daily irrigations on acute HTX. 20 acutely injured but stable trauma patients requiring a chest tube for HTX will be enrolled. Patients will be assigned a 28Fr or 14 Fr chest tube with serial lavage and drainage. The endpoints will be HTX volume (by CT scan), complications, additional interventions, hospital length of stay, chest tube duration, provider feedback, and patient-reported outcomes.
CONDITIONS
Official Title
Traumatic Hemothorax Drainage and Daily Lavage
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to provide consent for the research study
- Age 15 years or older
- Acute traumatic hemothorax or hemothorax-pneumothorax diagnosed by chest CT within 24 hours of injury
- Clinical need for drainage with moderate or large hemothorax (greater than 300 mL)
- Hemodynamically stable (heart rate under 120 bpm, systolic blood pressure above 90 mmHg)
- Hemothorax volume greater than 300 mL by Mergo Formula from chest CT
- Ability to complete the full study including randomization, tube placement, lavages, and final CT scan
You will not qualify if you...
- Younger than 15 years
- Prisoners
- Pregnant individuals due to CT scan risks
- Hemothorax or hemothorax-pneumothorax not requiring drainage or already drained before enrollment
- Patients undergoing surgery such as thoracotomy as initial hemothorax treatment
- Persistent hemodynamic instability after initial resuscitation and CT imaging
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Penn Presbyterian Medical Center
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
Research Team
J
Jeremy W Cannon, MD
CONTACT
P
Phillp Kemp Bohan, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
2
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