Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT06066645

Travoprost Intraocular Implant + iStent Infinite vs. iStent Infinite Alone

Led by Glaukos Corporation · Updated on 2026-01-21

230

Participants Needed

1

Research Sites

228 weeks

Total Duration

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AI-Summary

What this Trial Is About

Adult subjects with elevated intraocular pressure who have successfully undergone placement of iStent infinite trabecular bypass system will be randomized to receive a travoprost intraocular implant or receive a sham procedure and be followed for 12 months.

CONDITIONS

Official Title

Travoprost Intraocular Implant + iStent Infinite vs. iStent Infinite Alone

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of open-angle glaucoma or ocular hypertension
  • Qualifying intraocular pressure in the study eye
  • Successful placement of the iStent infinite trabecular bypass system
  • Adults aged 18 years or older
Not Eligible

You will not qualify if you...

  • Unmedicated intraocular pressure greater than 36 mmHg in the study eye
  • Allergy or hypersensitivity to travoprost or components of the travoprost intraocular implant
  • Vertical cup/disc ratio greater than 0.8 in the study eye
  • Best corrected visual acuity worse than 20/80 in either eye
  • Any ocular disease or condition that may significantly increase risk, affect study results, or interfere with participation according to investigator judgment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Glaukos Clinical Study Site

Colorado Springs, Colorado, United States, 80907

Actively Recruiting

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Research Team

S

Study Director

CONTACT

S

Study Manager

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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