Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05736666

Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement

Led by University of Illinois at Chicago · Updated on 2026-02-10

196

Participants Needed

1

Research Sites

126 weeks

Total Duration

On this page

Sponsors

U

University of Illinois at Chicago

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn about preventing falls in people who have total knee replacement surgery using treadmill perturbation training. Perturbation training involves adjusting to rapid speed changes on a treadmill. The main questions it aims to answer are: * Does perturbation training improve the way that people who are planning to have total knee replacement surgery recover after treadmill test that reproduces a trip to the front or side? * Does perturbation training reduce the incidence of preventable gait-related falls during the first year after total knee replacement? Participants will: * complete surveys about their condition and fall history and take part in testing of walking ability and balance. * have a baseline gait analysis test to measure the motion of their body during normal walking. * Be randomized into two groups. One will receive fall-prevention literature. The other will receive the same literature and then take part in a two-week treadmill perturbation training program. * be contacted every two weeks for one year, and asked questions about whether they have fallen during that time. * wear a Fitbit activity monitor on their wrist for one year. Researchers will compare the number of falls from the group that only received literature to the treatment group to see if the training group has fewer falls during the year after surgery.

CONDITIONS

Official Title

Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of endstage knee osteoarthritis requiring total knee arthroplasty (TKA)
  • Scheduled for TKA within two months
  • Able to schedule and attend required training visits before surgery
Not Eligible

You will not qualify if you...

  • Dizziness or medical conditions affecting walking and balance such as stroke, multiple sclerosis, Parkinson's disease, positional vertigo, or Meniere's disease
  • Plans for contralateral TKA within 12 months
  • History of other lower extremity joint replacement within 5 years
  • Idiopathic low back pain
  • History of heart disease
  • Uncorrected vision impairment
  • Institutionalization

AI-Screening

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Trial Site Locations

Total: 1 location

1

Biomechanics and Clinical Outcomes Laboratory, University of Illinois Chicago

Chicago, Illinois, United States, 60612

Actively Recruiting

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Research Team

S

Study Coordinator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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