Actively Recruiting
TreaT-Assay: the New Frontier for the Diagnosis of Acute Rejection in Kidney Transplantation
Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-01-30
150
Participants Needed
1
Research Sites
181 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Kidney transplantation is the standard therapy for end-stage renal disease. Acute rejection (AR) or chronic rejection along with reactive donor immunity, which counteracts organ acceptance, are among the greatest medical challenges in transplantation. In the posttransplantation setting, immunosuppressive drugs are administered to control or prevent immune reactions; however, the therapies have serious side effects. Retrospective studies have shown heterogeneous risk profiles with respect to post-transplant complications, such as AR or infection, suggesting the introduction of an individualized immunosuppressive regimen2,3,4. Biomarkers are needed for such individual therapies to discriminate between patients with different risk profiles.
CONDITIONS
Official Title
TreaT-Assay: the New Frontier for the Diagnosis of Acute Rejection in Kidney Transplantation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy adult blood donors providing anonymous samples
- Patients undergoing living or cadaveric kidney transplantation at St. Orsola Hospital
- Patients willing to participate in the study
You will not qualify if you...
- Patients under 18 years of age
- Patients unable to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Italy, 40135
Actively Recruiting
Research Team
G
Gaetano La Manna, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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