Study of Endoscopic and Surgical Treatments for Barretts Esophagus and Esophageal Cancer Outcomes

What this Trial Is About

This study focuses on patients with Barretts esophagus BE and esophageal adenocarcinoma EAC, including those with Barretts related neoplasia and esophageal cancer. It evaluates outcomes of endoscopic eradication therapies EET and other treatments in a prospective manner, aiming to improve patient care and understand long-term effects and risks associated with Barretts esophagus and related cancers. Participants receive treatments based on their condition patients with Barretts related dysplasia or neoplasia undergo endoscopic eradication therapies such as mucosal resection, radiofrequency ablation, and cryotherapy. Those with invasive esophageal cancer receive treatments like surgery esophagectomy, chemotherapy, radiation, or palliative care. The study collects detailed treatment information including advanced imaging, tissue sampling, and any complications related to procedures or surgeries. During the study, patients provide demographic and medical history data, complete questionnaires on gastroesophageal reflux disease GERD symptoms and quality of life, and undergo endoscopic and histopathological evaluations. Researchers track outcomes over five years, including treatment effectiveness, recurrence rates, adverse events, and healthcare utilization. This long-term monitoring aims to assess overall improvements and durability of therapies while documenting risk factors and imaging impacts.

TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)