Actively Recruiting
Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation
Led by University of California, San Francisco · Updated on 2025-07-15
30
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
Sponsors
U
University of California, San Francisco
Lead Sponsor
H
Hearst Foundations
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a pilot study to examine the tolerability, safety and early efficacy of two forms of transcranial magnetic stimulation (TMS) for treating adolescents with Obsessive Compulsive Disorder (OCD) who have experienced limited improvements with usual treatments for OCD in adolescents. The project's primary goal is to examine whether adolescents can complete 3 consecutive weeks of TMS administered 5 days per week, and to describe the type of and how common individual side effects with TMS occur in adolescents with OCD. Participants will: * visit the clinic every weekday for 3 weeks (15 days) to receive TMS treatments * have a brain MRI scan before TMS treatments begins and after finishing all TMS * complete questionnaires and report changes in behavior and physical symptoms
CONDITIONS
Official Title
Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Outpatients aged 13 to 17 years
- Meets current DSM-5 criteria for Obsessive Compulsive Disorder with a CY-BOCS II score greater than 16 (moderate to severe)
- Stable on psychotropic medications and/or therapy for at least 8 weeks prior to the study and agrees to continue without changes during the study
- Able to continue medications and record daily usage throughout the study
- Capacity to provide informed assent and parent or legal guardian able to provide consent
- Able to tolerate clinical study procedures
- Successfully complete screening forms without contraindications
You will not qualify if you...
- History of schizophrenia, bipolar disorder, substance or alcohol abuse disorder, current elevated suicide risk, prior psychosurgery, or prior electroconvulsive therapy (ECT)
- Severe neurocognitive disorder, seizure disorder, or certain structural brain lesions such as intracranial masses, hydrocephalus, meningitis sequelae, or brain injury
- Contraindications to TMS including implanted devices, metal in the head or eyes (excluding dental implants), certain tics, medications or illnesses increasing seizure risk, or family history of seizure disorder in a first-degree relative
- Unstable physical, systemic, or metabolic disorders such as unstable hypertension or malnutrition from eating disorders
- Female participants who are pregnant or nursing
- Current or expected treatment with prohibited medications
- Inability to complete the research protocol as determined by the Principal Investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California, San Francisco
San Francisco, California, United States, 94107
Actively Recruiting
Research Team
S
Starlette Khim, BA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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