Using Negative Pressure Wound Therapy to Reduce Complications After Emergency Abdominal Surgery

What this Trial Is About

This clinical trial investigates the use of Negative Pressure Wound Therapy NPWT in adults undergoing emergency laparotomy surgeries. The main aim is to determine if NPWT can reduce wound complications such as surgical site infections, wound dehiscence, and seromas compared to regular dressings. The study involves randomizing patients to either NPWT or standard dressings at the time of skin closure, with no other changes to their care. Participants will receive either the Avance Solo NPWT system, which uses suction to clear fluids from the wound for 7 days after surgery, or standard postoperative dressings like Mepilex Border Post-Op. The treatment period lasts for 7 days, and patients are followed up at 14, 30 days, and 1 year. Follow-up includes visits, surveys, and an optional CT scan to assess incisional hernia formation. Throughout the study, participants will undergo assessments including wound complication monitoring at 14 and 30 days, quality of life and scar satisfaction surveys, and evaluation of infections, reoperations, and healthcare use. Some secondary outcomes track long-term events like hernias or bowel obstructions up to 5 years. The total study duration extends to 10 years, ensuring thorough long-term safety and effectiveness monitoring.

Treating Emergency Laparotomy Incisions With Negative Pressure Wound Therapy