Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07003906

Treating Emergency Laparotomy Incisions With Negative Pressure Wound Therapy

Led by Uppsala University · Updated on 2025-12-26

720

Participants Needed

6

Research Sites

519 weeks

Total Duration

On this page

Sponsors

U

Uppsala University

Lead Sponsor

U

Uppsala County Council, Sweden

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to investigate Negative Pressure Wound Therapy (NPWT) in adults undergoing emergency laparotomy. The main question it aims to answer is: Does NPWT decrease wound complications? Researchers will compare it against regular dressings to see if NPWT is superior.

CONDITIONS

Official Title

Treating Emergency Laparotomy Incisions With Negative Pressure Wound Therapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years old or older
  • Able to provide written informed consent
  • Undergoing emergency laparotomy
  • Having a midline incision longer than 10 cm with primary skin closure
Not Eligible

You will not qualify if you...

  • Unable to give consent due to dementia, impaired cognitive function, or unconsciousness
  • Investigator assesses subject cannot be followed up
  • Allergy to dressing materials
  • Pregnant or breastfeeding (females of childbearing potential)
  • Previously enrolled in this study
  • Expected reoperation within 28 days of the laparotomy
  • Emergency laparotomy performed within the last 3 months

AI-Screening

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Trial Site Locations

Total: 6 locations

1

Mälar Hospital

Eskilstuna, Sweden

Not Yet Recruiting

2

Linköping University Hospital

Linköping, Sweden

Not Yet Recruiting

3

Mora Hospital

Mora, Sweden

Not Yet Recruiting

4

Vrinnevi Hospital

Norrköping, Sweden

Not Yet Recruiting

5

Uppsala University Hospital

Uppsala, Sweden, 75185

Actively Recruiting

6

Västmanlands Hospital Västerås

Västerås, Sweden

Not Yet Recruiting

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Research Team

E

Erik Osterman, MD PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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