Actively Recruiting
Treating Loneliness In The Older Adult With Depression With tDCS
Led by Guangzhou Psychiatric Hospital · Updated on 2024-10-26
180
Participants Needed
1
Research Sites
113 weeks
Total Duration
On this page
Sponsors
G
Guangzhou Psychiatric Hospital
Lead Sponsor
T
The University of Hong Kong
Collaborating Sponsor
AI-Summary
What this Trial Is About
High loneliness is prevalent among older adults and is a significant risk factor for major depression and low recovery rates in patients. Current interventions for loneliness are limited. Previous research has demonstrated a link between loneliness, negative social emotions, and reduced resting-state functional connectivity in the lateral prefrontal cortex (LPFC) and the default mode network (DMN). Transcranial direct current stimulation (tDCS) has shown promise in enhancing emotional regulation and connectivity, potentially alleviating loneliness in older adults with depression.
CONDITIONS
Official Title
Treating Loneliness In The Older Adult With Depression With tDCS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- High loneliness as measured by a UCLA Loneliness Scale score greater than 43
- Diagnosis of major depressive disorder confirmed by the Structured Clinical Interview for DSM-5 Disorders
- No suicidal ideation with a Hamilton Depression Scale item 3 score of 1 or less
You will not qualify if you...
- Severe neurological diseases
- Bipolar disorder, schizophrenia, addiction, or impulse control disorders
- Contraindications for tDCS or MRI such as metal implants
- Presence of suicidal ideation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Guangzhou Brain Hospital
Guangzhou, Guangdong, China, 510370
Actively Recruiting
Research Team
K
Kangguang Lin, PhD; MD
CONTACT
R
Robin Shao, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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