Actively Recruiting
Treating Mild Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation
Led by The University of Texas at Dallas · Updated on 2025-09-23
136
Participants Needed
1
Research Sites
269 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., presupplementary motor area) thought to aid in memory will improve verbal retrieval in military veteran participants with histories of traumatic brain injuries. The primary outcome measures are neuropsychological assessments of verbal retrieval, and the secondary measures are neuropsychological assessments of other cognitive abilities and electroencephalography (EEG) measures. Additionally, the study will examine the degree to which baseline assessments of cognition and concussion history predict responses to treatment over time, both on assessments administered within the intervention period and at follow-up.
CONDITIONS
Official Title
Treating Mild Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants aged 18 to 75 years
- Previous service in the US armed services
- History of mild to moderate traumatic brain injury with verbal retrieval deficits confirmed by neuropsychological testing
- Traumatic brain injury evaluated by the Ohio State TBI Identification Method
- Fluent in speaking and reading English
You will not qualify if you...
- History of psychological or neurological disorders including dementia, epilepsy, severe traumatic brain injury, post-traumatic stress disorder, brain tumor, drug abuse, stroke, blood vessel abnormalities in the brain, Parkinson's disease, Huntington's disease, or multiple sclerosis
- Unable to give informed consent
- Cranial implants or skull defects that affect tDCS administration
- Use of medications that may interact with tDCS effects such as anti-convulsants, amphetamines, L-dopa, carbamazepine, sulpiride, pergolide, lorazepam, rivastigmine, dextromethorphan, D-cycloserine, flunarizine, ropinirole, or citalopram
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The University of Texas at Dallas
Dallas, Texas, United States, 75235
Actively Recruiting
Research Team
A
Ashna Adhikari
CONTACT
J
Jill Ritter, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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