Actively Recruiting
Treating Polysubstance Use Using a Novel Digital Technology
Led by Friends Research Institute, Inc. · Updated on 2025-12-15
240
Participants Needed
5
Research Sites
218 weeks
Total Duration
On this page
Sponsors
F
Friends Research Institute, Inc.
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to determine the effects of an app to reduce opioid and cocaine use when layered atop methadone treatment as usual among people using both opioids and cocaine. The main questions it aims to answer are: * Do people who use the app remain in methadone treatment longer than people who receive only treatment as usual? * Do people who use the app report using opioids and/or cocaine less often, and do they report better improvements in their quality of life, than people who receive only treatment as usual? * Does using the app more lead to better methadone treatment outcomes among people using the app? Participants in this study will be randomly assigned to receive either the app or methadone treatment as usual. Participants randomly assigned to the treatment as usual group will receive access to methadone services as normally provided, including scheduled access to medications, information about the consequences of opioid and other drug use, and any onsite services (including group based interventions and/or 12-step programs). Those randomized into the app-using group will receive all the same services as the treatment as usual group, but will also be given a phone with the app already installed, or will have the app installed on their existing phone if they already have one. At random times throughout the week, the app will ask participants to submit drug tests for opioids and cocaine, which participants will be able to do remotely without having to physically "go to" a testing site. For each test that demonstrates the participant hasn't used opioids or cocaine, the participant will be rewarded with money directly into a debit card. Participants will also be able to earn rewards for picking up treatment-related medications, attending onsite appointments, and other treatment-related activities.
CONDITIONS
Official Title
Treating Polysubstance Use Using a Novel Digital Technology
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 or older
- Self-reported cocaine use in the past 30 days
- Willing and able to provide informed consent
You will not qualify if you...
- Severe psychiatric disorders
- On home detention
- Visual impairment making phone app use impractical
- Living arrangements that restrict phone access
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Friends Research Institute, Inc. Central Office
Baltimore, Maryland, United States, 21201
Actively Recruiting
2
Glenwood Life Counseling Center
Baltimore, Maryland, United States, 21212
Actively Recruiting
3
Institutes for Behavior Resources
Baltimore, Maryland, United States, 21218
Actively Recruiting
4
Man Alive
Baltimore, Maryland, United States, 21218
Actively Recruiting
5
BD Health Services, Inc. -- Dundalk
Baltimore, Maryland, United States, 21222
Actively Recruiting
Research Team
K
Karen Alexander, Ph.D.
CONTACT
J
Jesse B Fletcher, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here