Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT05766631

Treating Polysubstance Use Using a Novel Digital Technology

Led by Friends Research Institute, Inc. · Updated on 2025-12-15

240

Participants Needed

5

Research Sites

218 weeks

Total Duration

On this page

Sponsors

F

Friends Research Institute, Inc.

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to determine the effects of an app to reduce opioid and cocaine use when layered atop methadone treatment as usual among people using both opioids and cocaine. The main questions it aims to answer are: * Do people who use the app remain in methadone treatment longer than people who receive only treatment as usual? * Do people who use the app report using opioids and/or cocaine less often, and do they report better improvements in their quality of life, than people who receive only treatment as usual? * Does using the app more lead to better methadone treatment outcomes among people using the app? Participants in this study will be randomly assigned to receive either the app or methadone treatment as usual. Participants randomly assigned to the treatment as usual group will receive access to methadone services as normally provided, including scheduled access to medications, information about the consequences of opioid and other drug use, and any onsite services (including group based interventions and/or 12-step programs). Those randomized into the app-using group will receive all the same services as the treatment as usual group, but will also be given a phone with the app already installed, or will have the app installed on their existing phone if they already have one. At random times throughout the week, the app will ask participants to submit drug tests for opioids and cocaine, which participants will be able to do remotely without having to physically "go to" a testing site. For each test that demonstrates the participant hasn't used opioids or cocaine, the participant will be rewarded with money directly into a debit card. Participants will also be able to earn rewards for picking up treatment-related medications, attending onsite appointments, and other treatment-related activities.

CONDITIONS

Official Title

Treating Polysubstance Use Using a Novel Digital Technology

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 or older
  • Self-reported cocaine use in the past 30 days
  • Willing and able to provide informed consent
Not Eligible

You will not qualify if you...

  • Severe psychiatric disorders
  • On home detention
  • Visual impairment making phone app use impractical
  • Living arrangements that restrict phone access

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 5 locations

1

Friends Research Institute, Inc. Central Office

Baltimore, Maryland, United States, 21201

Actively Recruiting

2

Glenwood Life Counseling Center

Baltimore, Maryland, United States, 21212

Actively Recruiting

3

Institutes for Behavior Resources

Baltimore, Maryland, United States, 21218

Actively Recruiting

4

Man Alive

Baltimore, Maryland, United States, 21218

Actively Recruiting

5

BD Health Services, Inc. -- Dundalk

Baltimore, Maryland, United States, 21222

Actively Recruiting

Loading map...

Research Team

K

Karen Alexander, Ph.D.

CONTACT

J

Jesse B Fletcher, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here