Actively Recruiting
Treating Postictal Symptoms Using Ibuprofen and Nifedipine
Led by University of Calgary · Updated on 2024-05-09
90
Participants Needed
2
Research Sites
212 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will evaluate the effect of ibuprofen or nifedipine on post-seizure hypoperfusion and neurological deficits in patients with epilepsy. One group will receive ibuprofen, another will receive nifedipine, and anther placebo.
CONDITIONS
Official Title
Treating Postictal Symptoms Using Ibuprofen and Nifedipine
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than 16 years
- Frequent seizures occurring more than once per week
- Cognitive ability sufficient to complete neuropsychological testing
You will not qualify if you...
- Multiple seizure onset zones
- Contraindications to CT or MR imaging
- Contraindications to ibuprofen or nifedipine
- Current or recent exposure (within 2 months) to COX-2 inhibitors or calcium channel blockers
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Foothills Medical Centre
Calgary, Alberta, Canada, T2N T29
Actively Recruiting
2
South Health Campus
Calgary, Alberta, Canada, T3M 1M4
Actively Recruiting
Research Team
P
Paolo Federico, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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