Actively Recruiting
Treatment of Acute Ischemic StroKe With Intravenous UroKinase Real-world Research: a Multicenter, Prospective Study
Led by The First Affiliated Hospital of Zhengzhou University · Updated on 2024-01-08
1800
Participants Needed
16
Research Sites
152 weeks
Total Duration
On this page
Sponsors
T
The First Affiliated Hospital of Zhengzhou University
Lead Sponsor
T
Techpool Bio-Pharma Co., Ltd.
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to to compare the safety and effectiveness of IV urokinase with IV alteplase in the treatment of AIS in patients up to 6 hours from symptom onset.
CONDITIONS
Official Title
Treatment of Acute Ischemic StroKe With Intravenous UroKinase Real-world Research: a Multicenter, Prospective Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Clinical diagnosis of acute ischemic stroke with sudden onset of focal neurologic deficit or language impairment lasting over 24 hours
- Imaging confirms ischemic stroke and excludes hemorrhage or non-vascular causes
- First-time stroke or history of stroke with baseline modified Rankin Scale score 1 or less
- Eligible for intravenous urokinase or alteplase treatment as assessed by investigators
- Willing to participate and sign informed consent or have consent from legally authorized representative
You will not qualify if you...
- Contraindications for thrombolysis according to 2018 Chinese Guidelines
- Female of childbearing potential who is pregnant, breastfeeding, or has a positive pregnancy test at admission
- History of drug abuse or addiction in the past year
- Expected survival less than 90 days due to severe diseases or cancer
- Unable to follow study protocol due to mental illness or cognitive disorder
- Participation in any interventional drug or device trial within 3 months prior to screening
- Considered unsuitable for the study by investigators
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 16 locations
1
The First People's Hospital of Lanzhou City
Lanzhou, Gansu, China, 730000
Not Yet Recruiting
2
Affiliated Hospital of Guangdong Medical University
Zhanjiang, Guangdong, China, 524000
Not Yet Recruiting
3
Beiliu People's Hospital
Beiliu, Guangxi, China, 537400
Not Yet Recruiting
4
Guidong People's Hospital of Guangxi zhuang Autonomous Region
Guidong, Guangxi, China, 546612
Not Yet Recruiting
5
Tengxian People's Hospital
Wuzhou, Guangxi, China, 543300
Not Yet Recruiting
6
Red Cross Hospital of Yulin City
Yulin, Guangxi, China, 537000
Not Yet Recruiting
7
The First People's Hospital of Yulin
Yulin, Guangxi, China, 537099
Not Yet Recruiting
8
Sanya People's Hospital
Sanya, Hainan, China, 57200
Not Yet Recruiting
9
The First Affiliated Hospital of Jiamusi University
Jiamusi, Heilongjiang, China, 154002
Not Yet Recruiting
10
The People's Hospital of Anyang City
Anyang, Henan, China, 455000
Not Yet Recruiting
11
Kaifeng Central Hospital
Kaifeng, Henan, China, 475000
Not Yet Recruiting
12
The Second People's Hospital of Mengjin District
Luoyang, Henan, China, 471100
Not Yet Recruiting
13
Pingdingshan The Second People's Hospital
Pingdingshan, Henan, China, 467000
Not Yet Recruiting
14
The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China, 0371
Actively Recruiting
15
Huiji District People's Hospital
Zhengzhou, Henan, China, 450053
Not Yet Recruiting
16
Affiliated Hospital of Inner Mongolia Minzu University
Tongliao, Inner Mongolia, China, 028000
Not Yet Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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