Actively Recruiting
Treatment of AD With IgE Specific Immunoadsorption (IGEIAAD)
Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2024-07-15
15
Participants Needed
1
Research Sites
591 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Removal of IgE through adsorption of IgE on a specially designed column after apheresis of blood has the potential to improve the severity of atopic dermatitis. In this study the investigators will treat patients with a severe form of Atopic dermatitis not responding or having to much side effects to systemic imunosuppressive treatment with this modality.
CONDITIONS
Official Title
Treatment of AD With IgE Specific Immunoadsorption (IGEIAAD)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults older than 18 years with severe atopic dermatitis (objective SCORAD greater than 40)
- Atopic dermatitis that has been persistent and stable for more than 1 year
- Signed informed consent to participate
- Not pregnant and not planning pregnancy during immunoadsorption treatment
- Previously treated with phototherapy or immunosuppressive therapies (such as cyclosporin A, methotrexate, azathioprine, mycophenolate, systemic corticosteroids) that were ineffective, caused unacceptable side effects, or were contraindicated
You will not qualify if you...
- Did not give informed consent
- Have mild or moderate atopic dermatitis
- Have severe atopic dermatitis that improves with and tolerates standard therapies without contraindications
- Pregnant women or women planning pregnancy during or immediately after treatment
- Contraindications to immunoadsorption including allergy to treatment materials, severe cardiovascular disease, severe bleeding during anticoagulation, treatment with ACE inhibitors, or being under 18 years old
- Having an active malignant disease not in remission
AI-Screening
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Trial Site Locations
Total: 1 location
1
UZ Leuven
Leuven, Belgium, 3000
Actively Recruiting
Research Team
M
Marie-Anne C Morren, MD
CONTACT
B
Björn Meijers, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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