Actively Recruiting
Treatment for Antepartum Posttraumatic Stress Disorder/PTSD Study
Led by Boston University · Updated on 2025-05-30
240
Participants Needed
1
Research Sites
230 weeks
Total Duration
On this page
Sponsors
B
Boston University
Lead Sponsor
E
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The majority of women with perinatal posttraumatic stress disorder (PTSD) do not receive mental health treatment despite the documented associations between PTSD and adverse pregnancy outcomes; this is likely due to workforce shortages, lack of data on the effectiveness of existing evidence-based treatment for PTSD in usual care obstetrics settings, and patient-level barriers to engagement such as stigma. The proposed study is a randomized controlled trial, which will examine the effectiveness of a brief evidence-based treatment for PTSD (i.e., Written Exposure Therapy) during pregnancy and the non-inferiority of delivery of this treatment by community health workers vs. delivery by mental health clinicians.
CONDITIONS
Official Title
Treatment for Antepartum Posttraumatic Stress Disorder/PTSD Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pregnant woman receiving prenatal care at BMC Obstetrics and Gynecology Department
- Presenting for prenatal care prior to gestational age of 28 weeks
- Meet diagnostic or subthreshold criteria for PTSD on the Clinician Administered PTSD Scale for DSM-5 (CAPS-5)
You will not qualify if you...
- Clinician judgment that the patient is not appropriate for outpatient level care
- Current psychosis or unstable bipolar disorder diagnosis
- Currently receiving exposure-based PTSD treatment elsewhere
- Current incarceration preventing mental health care outside correctional facility
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Boston Medical Center and remote
Boston, Massachusetts, United States, 02118
Actively Recruiting
Research Team
Y
Yael I Nillni, PhD
CONTACT
H
Hannah Brown, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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