Actively Recruiting

Phase Not Applicable
Age: 18Years - 55Years
All Genders
NCT04184687

The Treatment of Cartilaginous Lesions and Concomitant Anterior Cruciate Ligament Reconstruction

Led by Istituto Ortopedico Rizzoli · Updated on 2025-05-18

88

Participants Needed

1

Research Sites

417 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of the study is the evaluation of both clinical and radiological results in patients undergone to cruciate ligament reconstruction with concomitant cartilaginous lesion treated with or without nanofractures.

CONDITIONS

Official Title

The Treatment of Cartilaginous Lesions and Concomitant Anterior Cruciate Ligament Reconstruction

Who Can Participate

Age: 18Years - 55Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female patients, 18 < age < 55
  • Complete ACL injury candidates for surgical reconstruction
  • Cartilaginous lesion of femur-tibial compartment grade III-IV ICRS ≤3 cm2 confirmed during surgery
  • No evidence of osteoarthritis
  • Ability and consent to participate in clinical and radiological follow-up
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Incapable of understanding or consenting
  • Immunodepression
  • Malignant neoplasms
  • Rheumatic diseases
  • Non-compensated diabetes
  • Uncompensated thyroid metabolic disorders
  • Abuse of alcohol or drugs
  • Axial deviations greater than 5°
  • Body Mass Index over 35
  • Surgery on the same knee within previous 12 months
  • Cartilaginous lesions grade I-II by ICRS score
  • Cartilage lesions larger than 3 cm²
  • Non-suturable meniscal lesions requiring meniscectomy over 50% or previous meniscectomies over 50% in same compartment
  • Need for additional surgical procedures beyond ACL reconstruction and possible nanofractures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Istituto Ortopedico Rizzoli

Bologna, Italy

Actively Recruiting

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Research Team

A

Alessandro Di Martino

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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The Treatment of Cartilaginous Lesions and Concomitant Anterior Cruciate Ligament Reconstruction | DecenTrialz