Prospective Multicenter Study on Treatment Effectiveness for Asymptomatic Common Bile Duct Stones

What this Trial Is About

This research aims to identify the characteristics of asymptomatic common bile duct stones and evaluate the effectiveness of their treatment. The study focuses on patients who have common bile duct stones detected incidentally during health screenings without symptoms. It addresses the lack of prospective studies comparing outcomes for those who undergo stone removal versus those who do not, especially concerning quality of life and risk of cholangitis. The study is conducted across multiple centers and sponsored by Kyungpook National University Hospital. Participants diagnosed with common bile duct stones through imaging may choose to undergo removal via endoscopic retrograde cholangiopancreatography, a procedure to remove the stones. Those who opt out of this treatment will be followed to monitor potential complications and the rate of cholangitis. The study will also assess the complication rates associated with this endoscopic procedure in asymptomatic patients. During the study, participants will complete questionnaires before and after treatment to measure quality of life changes, with primary outcomes assessed at three months. Researchers will monitor patients who decline removal for signs of cholangitis and complications. The total duration of follow-up and assessments will help determine the effectiveness and safety of treatment strategies for asymptomatic common bile duct stones.

The Treatment Effect for Asymptomatic Common Bile Duct Stone