Actively Recruiting
Treatment Efficacy of Regimens With and Without Bismuth in Children With Helicobacter Pylori-Associated Peptic Ulcer Disease
Led by Can Tho University of Medicine and Pharmacy · Updated on 2025-12-02
80
Participants Needed
1
Research Sites
86 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if including bismuth in the treatment helps heal stomach and duodenal ulcers caused by Helicobacter pylori (H. pylori) in children. The main questions it aims to answer are: * Does a treatment plan with bismuth work better than a plan without bismuth to clear the infection? * Is the bismuth plan more cost-effective while still safe and effective? Researchers will compare two treatment groups to see which works better. Participants will: * Take one of the two assigned treatment plans (with or without bismuth) for the standard treatment duration * Visit the clinic for checkups and tests to confirm infection clearance and monitor side effects * Keep a diary of symptoms, medication use, and any side effects
CONDITIONS
Official Title
Treatment Efficacy of Regimens With and Without Bismuth in Children With Helicobacter Pylori-Associated Peptic Ulcer Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with gastritis or peptic ulcer disease by upper gastrointestinal endoscopy or histopathology
- Meets diagnostic criteria for Helicobacter pylori infection
- Parent or legal guardian provides consent for the child to participate in the study
You will not qualify if you...
- Allergic to any medications in the treatment regimen
- Use of antibiotics or bismuth within the past 4 weeks, or use of antacids, H2-receptor antagonists, or proton pump inhibitors within the past 2 weeks
- Failure to return for follow-up visits after treatment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Can Tho Children's Hospital
Can Tho, Vietnam, 900000
Actively Recruiting
Research Team
T
Trang Thuy Mai, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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