Actively Recruiting
Treatment of Hypopigmented Scars With Bimatoprost
Led by Medstar Health Research Institute · Updated on 2024-05-03
25
Participants Needed
1
Research Sites
106 weeks
Total Duration
On this page
Sponsors
M
Medstar Health Research Institute
Lead Sponsor
L
Latham Fund
Collaborating Sponsor
AI-Summary
What this Trial Is About
Patients who have hypo-pigmented burn scar will have two scars chosen and randomized to treated scar and control scar. The subject will then have both scars treated with fractional ablative CO2 laser (FLSR). The treated scar will have bimatoprost delivered through the laser channels, while the control will have the vehicle (normal saline) only delivered. The treatment will continue for 14 days with twice daily application. The scars will then be monitored at a 2-week follow-up visit where levels of melanin will be evaluated. Tissue punch biopsies will also be used to evaluate the mechanism of action of bimatoprost. Treatment will occur for 6 sessions at 4-6 week intervals including follow- up visits and evaluations.
CONDITIONS
Official Title
Treatment of Hypopigmented Scars With Bimatoprost
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Cutaneous trauma resulting in hypopigmented scar
- Two different hypopigmented scars, each at least 30cm2, separated by at least 2 inches of normal skin, hyperpigmented scar, or hypopigmented scar
You will not qualify if you...
- Target hypopigmented scar located on face or genitalia
- Known allergy to bimatoprost
- Known allergy to lidocaine
- Positive urine pregnancy test in women of childbearing potential
- Lactating women
- Prisoner status
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
MedStar Washington Hospital Center
Washington D.C., District of Columbia, United States, 20010
Actively Recruiting
Research Team
A
Alison Ross, BA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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