Actively Recruiting

Phase Not Applicable
Age: 18Years - 84Years
All Genders
NCT04776473

Treatment of Intra-articular Fractures of the Mandibular Condyle

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2023-05-16

110

Participants Needed

7

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Intra-articular fractures of the mandibular condyle ((IAFC) are usually treated by means of physical therapy with or without transient maxillo-mandibular fixation (conservative or closed treatment). However, this can lead to incomplete manducatory function recovery due to limited mandibular mobility. During the last 15 years, a growing interest has emerged for open (surgical) treatment of these fractures. Although there is more and more evidence suggesting that the open treatment may be the treatment of choice for selected cases of subcondylar fractures, the best option remains controversial for high condylar fractures. The primary objective of the trial is to compare mandibular mobility at 3 months post-treatment between open (surgical) and closed (conservative) treatment of intra-articular fracture (high fracture) of the mandibular condyle. This study is an open multicenter randomized controlled trial with 2 parallel arms. Eligible patients will be randomized 1 :1 between open and closed-treatment group.

CONDITIONS

Official Title

Treatment of Intra-articular Fractures of the Mandibular Condyle

Who Can Participate

Age: 18Years - 84Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to under 85 years
  • Displaced non-comminuted intra-articular fracture of the mandibular condyle above the mandibular notch
  • Malocclusion and/or ramus shortening of 2 mm or more on CT scan (required if other facial fractures present)
  • Unilateral or bilateral fracture
  • Isolated or with other facial, skeletal, dental, or soft tissue injuries
  • Treatment planned within 14 days after trauma
  • Affiliated to a social security system (except AME)
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Contraindication to surgical treatment for any medical or anatomical reason
  • Major teeth loss or edentulous preventing occlusion assessment
  • History of mandibular fracture
  • History of temporo-mandibular joint disorder
  • Dentofacial dysmorphosis causing significant malocclusion
  • Expected inability to comply with follow-up
  • Unconsciousness or severe polytrauma
  • Participation in another interventional study

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 7 locations

1

CHU Angers

Angers, France

Not Yet Recruiting

2

Hôpital Annecy Genevois

Annecy, France, 74370

Not Yet Recruiting

3

APHM - Hôpital de la Conception

Marseille, France, 13005

Not Yet Recruiting

4

CHU de Nantes

Nantes, France, 44093

Not Yet Recruiting

5

Hôpital Pitié-Salpêtrière

Paris, France, 75013

Actively Recruiting

6

Hôpitaux Universitaires de Strasbourg

Strasbourg, France, 67200

Not Yet Recruiting

7

CHU Purpan - Hôpital Pierre-Paul Riquet

Toulouse, France, 31300

Not Yet Recruiting

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Research Team

T

Thomas SCHOUMAN, MD

CONTACT

M

Mourad BENASSAROU, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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