Actively Recruiting

Phase 4
Age: 25Years - 85Years
All Genders
NCT05582837

Treatment of Meniere's Disease With Migraine Medications

Led by University of California, Irvine · Updated on 2026-04-13

40

Participants Needed

1

Research Sites

282 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Meniere's disease (MD) is a chronic disease with a variety of fluctuating signs and symptoms, which include vertigo, hearing loss, tinnitus (ringing noise in the ear), aural pressure (feeling of ear fullness), and disequilibrium (lack of stability). Vertigo represents one of the most common and distressing problems in MD patients, and it causes various somatic and psychological disorders that interfere with the patient's quality of life. Despite the large economic and emotional impact of symptoms in MD patients, there is no FDA-approved medication to treat this debilitating condition. As such, our objective in this study is to evaluate the therapeutic potential of novel medications in treating MD that have previously shown astonishing promise in our clinical practice.

CONDITIONS

Official Title

Treatment of Meniere's Disease With Migraine Medications

Who Can Participate

Age: 25Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with active or frequent Meniere's Disease
  • Male or female between the ages of 25 to 85 years
  • Must be compliant with the medication and attend study visits
  • Must be able to read and write in the English language to provide consenting
Not Eligible

You will not qualify if you...

  • Pregnancy (ruled out by urine pregnancy test for women of childbearing potential)
  • History of surgery for Meniere's Disease
  • History of adverse reaction to the prescribed medications
  • Medical conditions or history concerning to the clinical investigator
  • Presence of psychosis
  • Presence of neurological neoplasm
  • Any contraindications for the study medications preventing randomization

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California, Irvine Medical Center ENT Clinic (Pavilion 2)

Orange, California, United States, 92868

Actively Recruiting

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Research Team

H

Hamid R Djalilian

CONTACT

M

Mehdi Abouzari

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Treatment of Meniere's Disease With Migraine Medications | DecenTrialz