Characteristics of participants at baseline in the Treatment of Mild Hypertension Study (TOMHS).
S R Mascioli, R H Grimm, J D Neaton...
https://pubmed.ncbi.nlm.nih.gov/2220647Completed
Phase 2
Age: 45Years - 69Years
All Genders
ID00000522
Led by University of Minnesota · Updated on 2016-02-25
N/A
Participants Needed
N/A
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of Minnesota
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
To compare the effects of nonpharmacologic therapy alone with those of one of five active drug regimens combined with non-pharmacologic therapy, for long- term management of patients with mild hypertension.
CONDITIONS
Official Title
Treatment of Mild Hypertension Study (TOMHS)
Who Can Participate
Age: 45Years - 69Years
All Genders
Eligibility Criteria
You may qualify if you...
Men and women, ages 45 to 69, with mild hypertension (diastolic blood pressure of 90-99 mm Hg at two of three visits for untreated individuals. Patients who received drug therapy must have had a DBP less than 95 mm Hg two to four weeks after drug.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Site Locations not provided
Location information for this trial is currently unavailable.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
N/A
Allocation
RANDOMIZED
Model
N/A
Primary Purpose
TREATMENT
Number of Arms
0
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Published Research Related To This Trial
The treatment of mild hypertension study. A randomized, placebo-controlled trial of a nutritional-hygienic regimen along with various drug monotherapies. The Treatment of Mild Hypertension Research Group.
https://pubmed.ncbi.nlm.nih.gov/2064494Echocardiographic correlates of left ventricular structure among 844 mildly hypertensive men and women in the Treatment of Mild Hypertension Study (TOMHS).
P R Liebson, G Grandits, R Prineas...
https://pubmed.ncbi.nlm.nih.gov/8425295Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group.
J D Neaton, R H Grimm, R J Prineas...
https://pubmed.ncbi.nlm.nih.gov/8336373Treatment of mild hypertension. The more things change..
H R Black
https://pubmed.ncbi.nlm.nih.gov/8336380Ethnicity and renal disease: lessons from the Multiple Risk Factor Intervention Trial and the Treatment of Mild Hypertension Study.
J M Flack, J D Neaton, B Daniels...
https://pubmed.ncbi.nlm.nih.gov/8465834Lifestyle intervention: results of the Treatment of Mild Hypertension Study (TOMHS).
P J Elmer, R Grimm, B Laing...
https://pubmed.ncbi.nlm.nih.gov/7479629Background and design of the new U.S. trial on diet and drug treatment of "mild" hypertension (TOMHS).
J Stamler, R J Prineas, J D Neaton...
https://pubmed.ncbi.nlm.nih.gov/3296721Echocardiography in multicenter clinical trials: experience from the Treatment of Mild Hypertension Study.
G A Grandits, P R Liebson, S Dianzumba...
https://pubmed.ncbi.nlm.nih.gov/8001359Comparison of five antihypertensive monotherapies and placebo for change in left ventricular mass in patients receiving nutritional-hygienic therapy in the Treatment of Mild Hypertension Study (TOMHS).
P R Liebson, G A Grandits, S Dianzumba...
https://pubmed.ncbi.nlm.nih.gov/7828296