Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT06890260

The Treatment of Moderate to Severe Allergic Rhinitis With Electroacupuncture Combined With Microneedle Knife

Led by Pengfei Qiu · Updated on 2025-03-30

90

Participants Needed

1

Research Sites

142 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Based on the inclusion and exclusion criteria, patients with allergic rhinitis who meet the requirements are selected as trial subjects, and the efficacy is clarified in a randomized controlled design trial. We will Use the total nasal symptom score as the primary outcome index, serum chemokine, intercellular adhesion molecule-1, eosinophil cationic protein, total non-nasal symptom score, and rhinitis-related quality of life scale as secondary outcome indexes, and oral cetirizine hydrochloride tablets and nasal budesonide spray as the control group, the efficacy of the subjects in the electroacupuncture combined with microneedle knife group and the drug group will be observed respectively before treatment, after 2 weeks of treatment, after 4 weeks, 1 month follow-up after the end of treatment, and 3 months follow-up after the end of treatment. 4 weeks later, 1 month follow-up after the end of treatment and 3 months follow-up after the end of treatment.

CONDITIONS

Official Title

The Treatment of Moderate to Severe Allergic Rhinitis With Electroacupuncture Combined With Microneedle Knife

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical and laboratory diagnosis of moderate to severe allergic rhinitis
  • Aged 18 to 75 years, any gender or ethnicity
  • No antihistamines or nasal steroids taken within 1 month before enrollment
  • Voluntary participation with signed informed consent
  • Able to attend outpatient treatment for 4 weeks
Not Eligible

You will not qualify if you...

  • Atrophic rhinitis, hypertrophic rhinitis, vasomotor rhinitis, acute or chronic sinusitis, nasal polyps, severe septal deviation, eosinophilia non-allergic rhinitis
  • Other allergic diseases causing nasal symptoms such as asthma, urticaria, or colds
  • Serious cardiovascular, cerebrovascular, liver, kidney, or blood system diseases
  • Pregnant or breastfeeding women
  • Psychiatric patients
  • Patients with malignant tumors

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Zhejiang Hospital

Hangzhou, Zhejiang, China, 310030

Actively Recruiting

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Research Team

P

Pengfei Qiu

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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