Actively Recruiting

Phase 4
Age: 18Years - 60Years
All Genders
NCT05839652

Treatment of Orthostatic Hypotension in SCI

Led by James J. Peters Veterans Affairs Medical Center · Updated on 2024-10-01

25

Participants Needed

2

Research Sites

156 weeks

Total Duration

On this page

Sponsors

J

James J. Peters Veterans Affairs Medical Center

Lead Sponsor

K

Kessler Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.

CONDITIONS

Official Title

Treatment of Orthostatic Hypotension in SCI

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Traumatic spinal cord injury
  • At least 12 months post injury
  • Injury level between C1 and T6
  • AIS A, B, or C classification
  • Non-ambulatory
  • Not using a ventilator
Not Eligible

You will not qualify if you...

  • Active psychiatric disorder
  • Stroke or cerebrovascular disease
  • Alzheimer's disease or dementia
  • Unmanaged cardiac arrhythmias
  • Concurrent systemic, hepatic, or renal disease
  • Suspected or diagnosed malignancy
  • Neurological disease other than spinal cord injury
  • History of three or more symptomatic episodes of autonomic dysreflexia per day

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Kessler Foundation

West Orange, New Jersey, United States, 07052

Actively Recruiting

2

James J Peters VA Medical Center

The Bronx, New York, United States, 10468

Actively Recruiting

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Research Team

M

Matt G. Maher, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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