Actively Recruiting
Treatment Outcomes and Complications of Three Therapeutic Approaches for Concomitant Choledocholithiasis and Cholecystolithiasis
Led by Qilu Hospital of Shandong University · Updated on 2026-02-17
300
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
Sponsors
Q
Qilu Hospital of Shandong University
Lead Sponsor
T
The Affiliated Hospital of Qingdao University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Recruit patients with cholelithiasis with concomitant choledocholithiasis into the cohort, and assign them to undergo endoscopic transpapillary gallbladder-preserving cholecystolithotomy or ERCP plus laparoscopic cholecystectomy or conservative treatment based on patient preference. Collect clinical data and patient-reported outcomes regularly at baseline and during follow-up in the cohort. Assess the clinical safety of ERCP-GPC and LC by evaluating the clinical success rate of treatment as well as the incidence of short-term and long-term postoperative complications; investigate the efficacy differences among endoscopic transpapillary gallbladder-preserving cholecystolithotomy or ERCP plus laparoscopic cholecystectomy or conservative treatment in managing cholelithiasis with concomitant choledocholithiasis.
CONDITIONS
Official Title
Treatment Outcomes and Complications of Three Therapeutic Approaches for Concomitant Choledocholithiasis and Cholecystolithiasis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients over the age of 18 years
- Diagnosis of cholelithiasis with choledocholithiasis confirmed by ultrasound, MRCP, CT, or MRI
- No history of gastrointestinal reconstruction surgery, cholecystectomy, or previous biliary tract surgery including ERCP
- Gallbladder stones are 1 cm in diameter or smaller, or sludge-like stones
- Gallbladder shape and size are normal, with wall thickness 3 mm or less
- Signed informed consent is provided voluntarily
You will not qualify if you...
- Atrophic cholecystitis, porcelain gallbladder, suspected gallbladder cancer, lower common bile duct stenosis, or Mirrizzi syndrome
- Unable to undergo endoscopic interventions
- Absolute surgical contraindications such as severe liver, kidney, heart, or lung failure, history of cerebral coma, or allergy to anesthesia
- Ectopic duodenal papilla or congenital pancreaticobiliary malformation
- Severe coagulopathy with INR greater than 1.5 or platelet count less than 50 x 10⁹/L
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Qilu Hospital of Shandong University
Jinan, Shandong, China, 250063
Actively Recruiting
Research Team
Z
Zhen Li, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here