Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT03929432

Treatment Outcomes With tDCS in Post-Stroke Aphasia

Led by University of Arkansas · Updated on 2025-07-17

50

Participants Needed

1

Research Sites

534 weeks

Total Duration

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AI-Summary

What this Trial Is About

The purpose this study is to test the utility of pairing external neuromodulation with behavioral language treatment to boost therapy outcomes and to investigate the mechanisms associated with recovery. Because all PWA have word retrieval deficits, this project will test if greater language gains can be achieved by supplementing anomia intervention with excitatory brain stimulation to the left hemisphere and will evaluate associated functional brain changes to aid the optimization of neural reorganization to facilitate language processing.

CONDITIONS

Official Title

Treatment Outcomes With tDCS in Post-Stroke Aphasia

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Presence of post-stroke aphasia
  • Single left hemisphere stroke etiology
  • At least 6 months post-stroke
  • Age range between 18 and 80 years old
  • Speak English as a native language
  • Adequate hearing and vision to complete the tasks
Not Eligible

You will not qualify if you...

  • Severe auditory comprehension deficits (e.g., global aphasia, Wernicke's aphasia, transcortical sensory aphasia)
  • Inability to provide informed consent
  • History of other neurological diseases or injuries (e.g., traumatic brain injury, right hemisphere stroke, dementia)
  • History of major mental illness (e.g., schizophrenia, drug addiction, bipolar disorder)
  • Clinical conditions not suitable for MRI or tDCS (e.g., implanted electrical devices, claustrophobia, seizure disorder)
  • Positive pregnancy test (for females)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Arkansas for Medical Sciences

Little Rock, Arkansas, United States, 72205

Actively Recruiting

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Research Team

D

Dana Moser, PhD, CCC-SLP

CONTACT

P

Portia Carr

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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