Actively Recruiting

Phase 2
Phase 3
Age: 18Years - 75Years
All Genders
NCT02657785

Treatment of PCNSL With R-IDARAM and Intrathecal Immunochemotherapy

Led by Navy General Hospital, Beijing · Updated on 2020-09-09

100

Participants Needed

1

Research Sites

1056 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study suggests that R-IDARAM combined with intrathecal immunochemotherapy may be high effective in primary central nervous system lymphoma (PCNSL) patients.

CONDITIONS

Official Title

Treatment of PCNSL With R-IDARAM and Intrathecal Immunochemotherapy

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Newly diagnosed histologically proven non-Hodgkin's lymphoma (NHL).
Not Eligible

You will not qualify if you...

  • Involved sites other than the brain, meninges, CSF, or the eyes.
  • Age less than 18 years or greater than 75 years.
  • Inadequate bone marrow capacity (neutrophils <1.5 �d710^9/L, platelets <100 �d710^9/L, hemoglobin <8 g/dL).
  • Known cause of immunosuppression (e.g., HIV type I infection).
  • Any previous malignancy.
  • Creatinine clearance below 60 mL/min.
  • Heart insufficiency (NYHA IIIB or IV).
  • Uncontrolled infection.
  • Noncompensated active pulmonary or liver disease.
  • Previously treated for PCNSL, except by corticosteroids.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Navy General Hospital

Beijing, Beijing Municipality, China, 100048

Actively Recruiting

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Research Team

L

Liren Qian, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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