Actively Recruiting
Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy
Led by Spaulding Rehabilitation Hospital · Updated on 2025-12-04
70
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is recruiting current or former athletes who had ACL reconstruction surgery over a year ago and have been diagnosed with knee osteoarthritis (OA). We are doing the research to investigate the effects of extracorporeal shockwave therapy (ESWT) on pain, function, biomechanics, knee range of motion and strength, inflammation, and joint structure and integrity of the knee.
CONDITIONS
Official Title
Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Previous ACL reconstruction using an autograft or allograft in the knee with post-traumatic osteoarthritis
- At least one year has passed since ACL reconstruction surgery
- Aged between 18 and 55 years
- No mechanical symptoms or contraindications that would limit ability to complete the study
- Knee Injury and Osteoarthritis Outcome Score (KOOS) score of 85 or lower in at least 2 of 4 domains: pain, symptoms, activities of daily living, or quality of life
- Primary pain is from the knee
- Diagnosis of post-traumatic osteoarthritis confirmed clinically and with radiographic evidence prior to enrollment
You will not qualify if you...
- Received injections to the knee joint within the past 3 months
- Pregnant women or those planning to become pregnant
- Neuropathy affecting pain sensation
- Known cardiac disease that could be affected by shockwave therapy
- Chronic rheumatological conditions, immunodeficiency, severe asthma, connective tissue disorders, or other medical conditions impacting inflammation or requiring chronic immune modulatory medications (mild asthma with inhaler use is allowed)
- Active use of oral steroids or anti-inflammatories at enrollment
- Bilateral ACL injury or reconstruction or ACL revision surgery
- Active malignancy or less than five years in remission
- Previous ESWT treatment with study devices for knee osteoarthritis
- Presence of pacemaker, bone screws, or metal implants that prevent MRI or ESWT participation
- Non-English speaking individuals
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Spaulding Cambridge Hospital
Cambridge, Massachusetts, United States, 02138
Actively Recruiting
Research Team
A
Adam S Tenforde, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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