Actively Recruiting
Treatment Response Assessment Maps to Delineate Necrosis From Tumor After Stereotactic Radiation in Brain Metastases
Led by Brigham and Women's Hospital · Updated on 2026-03-19
101
Participants Needed
2
Research Sites
462 weeks
Total Duration
On this page
Sponsors
B
Brigham and Women's Hospital
Lead Sponsor
D
Dana-Farber Cancer Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research study is investigating the value of an imaging study of the brain called an MRI (which stands for magnetic resonance imaging), utilized in unique way, to delineate whether the tumor has recurred or whether radiation changes have occurred after a brain metastasis treated with focused radiation has enlarged.
CONDITIONS
Official Title
Treatment Response Assessment Maps to Delineate Necrosis From Tumor After Stereotactic Radiation in Brain Metastases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have a confirmed solid cancer that started outside the brain and have at least one brain metastasis treated with stereotactic radiation
- Have an enlarging brain lesion at least 4 months after prior stereotactic radiation with planned neurosurgical resection
- Be 18 years of age or older
- Be willing to undergo study procedures
- Agree to use effective contraception during the study if of child-bearing potential
- Be able and willing to sign informed consent
You will not qualify if you...
- Have a contraindication to MRI, such as non-compatible implanted metallic devices
- Have chronic kidney disease stage IV or V or end-stage renal disease
- Have a history of severe allergic reaction to gadolinium contrast agents
- Are pregnant or breastfeeding
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
2
Dana Farber Cancer Institute
Boston, Massachusetts, United States, 02115
Actively Recruiting
Research Team
A
Ayal Aizer, MD, MHS
CONTACT
I
Ivy Ricca, BA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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