Actively Recruiting
Treatment Response Biomarkers in MDD
Led by Zhang Yan · Updated on 2022-10-19
480
Participants Needed
1
Research Sites
272 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This experiment intends to explore the differences among various types of depression, as well as the differences between healthy subjects and depressed patients, and find possible biological markers from the severity of symptoms, social function and cognitive function of depressed patients, combined with EEG characteristics, biological test indicators (blood, faeces, hair, etc.) and functional magnetic resonance imaging data. To explore the changes in clinical symptoms, cognitive and social functions, and biological indicators of various types of patients before and after treatment, to provide references for the prognosis of various types, and to predict the future development of the disease according to the baseline indicators of patients; According to the above aspects, this experiment can follow up the patients with depression, track their disease development, and study the potential biological changes in the early stage of the disease, which has the potential to reveal the pathogenesis and provide guidance for the early diagnosis and intervention of depression.
CONDITIONS
Official Title
Treatment Response Biomarkers in MDD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Outpatient or inpatient diagnosed with current or past Major Depressive Disorder by M.I.N.I. interview using DSM-5 criteria
- Aged 18 to 60 years, any gender
- Right-handed
- Education level of junior high school or above, able to complete informed consent and cognitive tests
- Willing to take antidepressant treatment as advised during follow-up period
You will not qualify if you...
- Presence of psychotic symptoms
- Diagnosed with schizophrenia, schizophrenic affective disorder, schizophrenia-like disorder, paranoia, PTSD (current or within past year), or dysthymia by M.I.N.I.
- Having serious brain organic or physical diseases (e.g., thyroid disease, lupus, diabetes, lung, liver, kidney damage, infection, major trauma), excluding intracranial implants
- Clinically significant sensory impairments that cannot be corrected (e.g., hearing loss preventing conversation)
- Pregnant or breastfeeding women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Central South University
Changsha, Hunan, China, 410001
Actively Recruiting
Research Team
Y
yan zhan, doctor
CONTACT
Y
yumeng ju, doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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