Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
NCT03312556

Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Led by Vanderbilt University Medical Center · Updated on 2025-11-06

12

Participants Needed

1

Research Sites

482 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of this study is to assess whether continuous positive airway pressure (CPAP) decreases blood pressure in autonomic failure patients with supine hypertension.

CONDITIONS

Official Title

Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with autonomic failure and with supine hypertension from all races
Not Eligible

You will not qualify if you...

  • All medical students
  • Pregnant women
  • High-risk patients (e.g. heart failure, symptomatic coronary artery disease, liver impairment, history of stroke or myocardial infarction)
  • History of serious allergies or asthma.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Autonomic Dysfunction Center/ Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37232

Actively Recruiting

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Research Team

B

Bonnie K Black, RN

CONTACT

L

Luis E Okamoto, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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