Actively Recruiting
Study of Tremor in Adults Aged 18 to 65 With Charcot-Marie-Tooth Disease and Healthy Controls
Led by University Medical Center Goettingen · Updated on 2026-05-06
75
Participants Needed
1
Research Sites
16 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying tremor in patients with Charcot-Marie-Tooth CMT disease to better understand its causes and impact. The study aims to clarify the nature of tremor in CMT patients and assess how much it affects their daily lives and quality of life. This observational research includes patients with and without tremor and explores possible genetic links and disease progression. The study involves collecting detailed clinical data from participants, including surface electromyography and accelerometer measurements to characterize tremor. Participants will undergo clinical examinations that are video-recorded by neurologists for careful analysis. A questionnaire will assess how tremor influences daily activities and the burden it causes. CMT patients without tremor will serve as controls. Participants will complete multiple assessments at the start of the study, including questionnaires on daily living activities and handicap, as well as tremor rating scales and electrophysiological tests. Additional motor function scales will also be collected. This helps researchers understand the severity and functional impact of tremor. The study runs until October 2026 and includes adults aged 18 to 65 who can consent and complete the assessments.
CONDITIONS
Brief Title
TREMOR IN CHARCOT-MARIE-TOOTH
Research Team
M
Michael W Sereda, Prof. MD
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