Actively Recruiting
Investigation of Tremor in Patients With Charcot-Marie-Tooth Neuropathy
Led by University Medical Center Goettingen · Updated on 2026-05-06
75
Participants Needed
1
Research Sites
16 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying tremor in patients with Charcot-Marie-Tooth (CMT) disease to better understand its causes and impact. The study aims to clarify the nature of tremor in CMT patients and assess how much it affects their daily lives and quality of life. This observational research includes patients with and without tremor and explores possible genetic links and disease progression. The study involves collecting detailed clinical data from participants, including surface electromyography and accelerometer measurements to characterize tremor. Participants will undergo clinical examinations that are video-recorded by neurologists for careful analysis. A questionnaire will assess how tremor influences daily activities and the burden it causes. CMT patients without tremor will serve as controls. Participants will complete multiple assessments at the start of the study, including questionnaires on daily living activities and handicap, as well as tremor rating scales and electrophysiological tests. Additional motor function scales will also be collected. This helps researchers understand the severity and functional impact of tremor. The study runs until October 2026 and includes adults aged 18 to 65 who can consent and complete the assessments.
CONDITIONS
Brief Title
TREMOR IN CHARCOT-MARIE-TOOTH
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of Charcot-Marie-Tooth disease or healthy control group
- Genetic confirmation of CMT in adult patients
- Ability to complete the baseline outcome measures
- Age between 18 and 65 years
- Capacity to consent and signed informed consent form
You will not qualify if you...
- Pregnancy or breastfeeding
- Other significant neurological or psychiatric disorders, current or past
- Serious previous internal diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants complete baseline assessments including questionnaires and electrophysiological tests to characterize tremor.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
University Medical Centre
Göttingen, Lower Saxony, Germany, 37075
Actively Recruiting
Research Team
M
Michael W Sereda, Prof. MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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