Actively Recruiting
The Triad of Nutrition, Intestinal Microbiota and Rheumatoid Arthritis (TASTY)
Led by Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa · Updated on 2025-01-06
100
Participants Needed
2
Research Sites
156 weeks
Total Duration
On this page
Sponsors
L
Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa
Lead Sponsor
G
Gulbenkian Institute for Molecular Medicine
Collaborating Sponsor
AI-Summary
What this Trial Is About
The main goal of this trial is to investigate whether a dietary intervention based on a typical Mediterranean Diet enriched with fermented foods (MedDiet+) can impact gut microbiota and RA-related outcomes.
CONDITIONS
Official Title
The Triad of Nutrition, Intestinal Microbiota and Rheumatoid Arthritis (TASTY)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with rheumatoid arthritis by ACR/EULAR 2010 criteria
- Age over 18 years
- Disease lasting more than 1 year
- Active rheumatoid arthritis with a DAS28 score above 2.6 units
- Stable medication for at least 12 weeks prior to study
- Low to medium adherence to Mediterranean Diet (PREDIMED score below 10)
- Willingness to follow the study protocol
You will not qualify if you...
- Taking prednisolone at doses of 7.5 mg/day or higher
- Use of antibiotics within 4 weeks before starting the study
- Regular use of NSAIDs
- Having inflammatory or irritable bowel diseases
- Diagnosis of celiac disease
- Experiencing chronic diarrhea
- Diagnosis of diabetes
- Other immune-mediated inflammatory diseases besides rheumatoid arthritis
- Major organ dysfunction
- Cancer diagnosed within the last five years
- Health conditions interfering with participation, such as cognitive impairment or psychiatric illness
- Being pregnant or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Unidade Local de Saude de Santa Maria
Lisbon, Portugal, Portugal, 1649-035
Actively Recruiting
2
Faculdade Medicina de Lisboa
Lisbon, Portugal, Portugal, 1800-268
Actively Recruiting
Research Team
C
Catarina Sousa Guerreiro, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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